Homogeneous Test-bed for Cognitive Radio

In the current frequency allocation scheme, the radio spectrum is found to be heavily underutilized in time, frequency and space dimensions or any of their combination. To improve spectrum utilization, the unused contiguous or non-contiguous portion of the radio spectrum (spectrum hole) can be accessed opportunistically using cognitive radio technology provided it is interference free to the local users of the network. To reliably detect the spectrum holes, which is necessary to limit the interference, cognitive radio is required to have high time and frequency resolutions to detect radio technologies (e.g. GSM 900, 2.4 GHz WLAN) at the packet level in the transmitted channel to avoid misinterpretation of occupancy states in time and frequency. In addition, having high sensitivity and instantaneous dynamic range can enable cognitive radio to detect weak received signals and their detection in the presence of strong received signals. Besides these requirements, a large sensing bandwidth can increase the chances to find spectrum holes in multiple radio technologies concurrently. A chirp channel sounder receiver has been developed according to the aforementioned requirements with a bandwidth of 750 MHz to provide reliable detection of received signals in two frequency ranges; 1) 250 MHz to 1 GHz, 2) 2.2 GHz to 2.95 GHz. The developed receiver is capable of finding spectrum holes having a duration of 204.8 μs and a transmitted channel bandwidth up to 200 kHz. To explore the spectrum holes in the space dimensions, six chirp channel sounder receivers have been developed to form a homogeneous test-bed, which can be deployed and controlled independently. To experimentally validate the ability of the built receiver, short term spectrum occupancy measurements have been conducted to monitor 2.4 GHz WLAN traffic from a real wireless network to quantify the spectrum utilization and duration of spectrum holes in the time domain. It has been found that the radio spectrum is underutilized and empirical distribution of the duration of the spectrum hole can be modelled using lognormal and gamma distributions for prediction using a two state continuous time semi-Markov model. To experimentally validate the receiver’s capabilities in both the supported frequency ranges, long term spectrum occupancy measurements with 750 MHz sensing bandwidth have been performed and received signals have been detected at frame or packet level to quantify spectrum utilization. It has been found that the radio spectrum is highly underutilized at the measurement location and exhibits significant amount of spectrum holes in both time and frequency. To experimentally validate the functionalities of the homogeneous test-bed, short term spectrum occupancy have been performed to monitor 2.4 GHz WLAN traffic from a real wireless network. The experiment has been conducted using multiple receivers to quantify the amount of cooperation individual or multiple cognitive radio users can provide for reliable detection of spectrum holes in time, frequency and space. It has been found that the space dimension influences strongly the statistics of cooperation parameters

Spectrum Occupancy Measurements and Analysis in 2.4 GHz WLAN

High time resolution spectrum occupancy measurements and analysis are presented for 2.4 GHz WLAN signals. A custom-designed wideband sensing engine records the received power of signals, and its performance is presented to select the decision threshold required to define the channel state (busy/idle). Two sets of measurements are presented where data were collected using an omni-directional and directional antenna in an indoor environment. Statistics of the idle time windows in the 2.4 GHz WLAN are analyzed using a wider set of distributions, which require fewer parameters to compute and are more practical for implementation compared to the widely-used phase type or Gaussian mixture distributions. For the omni-directional antenna, it was found that the lognormal and gamma distributions can be used to model the behavior of the idle time windows under different network traffic loads. In addition, the measurements show that the low time resolution and angle of arrival affect the statistics of the idle time window

A Deep Neural Network-Based Multi-Frequency Path Loss Prediction Model from 0.8 GHz to 70 GHz

Large-scale fading models play an important role in estimating radio coverage, optimizing base station deployments and characterizing the radio environment to quantify the performance of wireless networks. In recent times, multi-frequency path loss models are attracting much interest due to their expected support for both sub-6 GHz and higher frequency bands in future wireless networks. Traditionally, linear multi-frequency path loss models like the ABG model have been considered, however such models lack accuracy. The path loss model based on a deep learning approach is an alternative method to traditional linear path loss models to overcome the time-consuming path loss parameters predictions based on the large dataset at new frequencies and new scenarios. In this paper, we proposed a feed-forward deep neural network (DNN) model to predict path loss of 13 different frequencies from 0.8 GHz to 70 GHz simultaneously in an urban and suburban environment in a non-line-of-sight (NLOS) scenario. We investigated a broad range of possible values for hyperparameters to search for the best set of ones to obtain the optimal architecture of the proposed DNN model. The results show that the proposed DNN-based path loss model improved mean square error (MSE) by about 6 dB and achieved higher prediction accuracy R2 compared to the multi-frequency ABG path loss model. The paper applies the XGBoost algorithm to evaluate the importance of the features for the proposed model and the related impact on the path loss prediction. In addition, the effect of hyperparameters, including activation function, number of hidden neurons in each layer, optimization algorithm, regularization factor, batch size, learning rate, and momentum, on the performance of the proposed model in terms of prediction error and prediction accuracy are also investigated

Experimental Evaluation of Hybrid Fibre−Wireless System for 5G Networks

This article describes a novel experimental study considering a multiband fibre–wireless system for constructing the transport network for fifth-generation (5G) networks. This study describes the development and testing of a 5G new radio (NR) multi-input multi-output (MIMO) hybrid fibre–wireless (FiWi) system for enhanced mobile broadband (eMBB) using digital pre-distortion (DPD). Analog radio over fibre (A-RoF) technology was used to create the optical fronthaul (OFH) that includes a 3 GHz supercell in a long-range scenario as well as a femtocell scenario using the 20 GHz band. As a proof of concept, a Mach Zehnder modulator with two independent radio frequency waveforms modifies a 1310 nm optical carrier using a distributed feedback laser across 10 km of conventional standard single-mode fibre. It may be inferred that a hybrid FiWi-based MIMO-enabled 5G NR system based on OFH could be a strong competitor for future mobile haul applications. Moreover, a convolutional neural network (CNN)-based DPD is used to improve the performance of the link. The error vector magnitude (EVM) performance for 5G NR bands is predicted to fulfil the Third Generation Partnership Project’s (3GPP) Release 17 standards

Global, regional, and national burden of other musculoskeletal disorders, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021

Background Musculoskeletal disorders include more than 150 different conditions affecting joints, muscles, bones, ligaments, tendons, and the spine. To capture all health loss from death and disability due to musculoskeletal disorders, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) includes a residual musculoskeletal category for conditions other than osteoarthritis, rheumatoid arthritis, gout, low back pain, and neck pain. This category is called other musculoskeletal disorders and includes, for example, systemic lupus erythematosus and spondylopathies. We provide updated estimates of the prevalence, mortality, and disability attributable to other musculoskeletal disorders and forecasted prevalence to 2050. Methods Prevalence of other musculoskeletal disorders was estimated in 204 countries and territories from 1990 to 2020 using data from 68 sources across 23 countries from which subtraction of cases of rheumatoid arthritis, osteoarthritis, low back pain, neck pain, and gout from the total number of cases of musculoskeletal disorders was possible. Data were analysed with Bayesian meta-regression models to estimate prevalence by year, age, sex, and location. Years lived with disability (YLDs) were estimated from prevalence and disability weights. Mortality attributed to other musculoskeletal disorders was estimated using vital registration data. Prevalence was forecast to 2050 by regressing prevalence estimates from 1990 to 2020 with Socio-demographic Index as a predictor, then multiplying by population forecasts. Findings Globally, 494 million (95% uncertainty interval 431–564) people had other musculoskeletal disorders in 2020, an increase of 123·4% (116·9–129·3) in total cases from 221 million (192–253) in 1990. Cases of other musculoskeletal disorders are projected to increase by 115% (107–124) from 2020 to 2050, to an estimated 1060 million (95% UI 964–1170) prevalent cases in 2050; most regions were projected to have at least a 50% increase in cases between 2020 and 2050. The global age-standardised prevalence of other musculoskeletal disorders was 47·4% (44·9–49·4) higher in females than in males and increased with age to a peak at 65–69 years in male and female sexes. In 2020, other musculoskeletal disorders was the sixth ranked cause of YLDs globally (42·7 million [29·4–60·0]) and was associated with 83 100 deaths (73 600–91 600). Interpretation Other musculoskeletal disorders were responsible for a large number of global YLDs in 2020. Until individual conditions and risk factors are more explicitly quantified, policy responses to this burden remain a challenge. Temporal trends and geographical differences in estimates of non-fatal disease burden should not be overinterpreted as they are based on sparse, low-quality data.publishedVersio

The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age  6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score  652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701